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We'd like to understand how you use our websites in order to improve them. Register your interest. Diabetic ketoacidosis is the most common cause of morbidity and mortality in children with type I diabetes mellitus. The main cause of pediatric death is cerebral edema responsible for intracranial hypertension. Even if the pathophysiology remains unclear, some risk factors have been identified, principally due to the preexistent conditions, but also to iatrogenic events.
Improvement in epidemiologic, pathophysiologic and clinical knowledge has resulted in great progress in the management of ketoacidosis, thus reducing morbidity and mortality in the most recent series. Intracranial hypertension can be responsible for major brain impairment; however, most of the time, cerebral edema is subclinical. This highlights the importance of a systematic research for detecting primary signs of cerebral edema in all patients presenting ketoacidosis in order to improve their management.
We will review the principal aspects of management of pediatric ketoacidosis regarding diagnosis clinical and radiological with the development of transcranial doppler and treatments. The best guaranty to obtain a significant reduction in morbidity and mortality depends on the early recognition of type I diabetes mellitus, before ketoacidosis, which could be considered as a public health objective, which has already been reached in several countries.
This is a preview of subscription content, log in to check access. Levin DL Cerebral edema in diabetic ketoacidosis. Pediatr Crit Care Med — Arch Dis Child — N Engl J Med — A 5-year prospective pediatric experience in episodes. Arch Pediatr Adolesc Med — Diabetes Care — Pediatrics e—e Lawrence S, Cummings E, Gaboury I, et al Populationbased study of incidence and risk factors for cerebral edema in pediaric diabetic ketoacidosis. J Pediatr — Pediatr Diabetes — Edge JA, Roy Y, Bergomi A, et al Conscious level in children with diabetic ketoacidosis is related to severity of acidosis and not to blood glucose concentration.
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Eskandar EN, Weller SJ, Frim DM Hydrocephalus requiring urgent external ventricular drainage in a patient with diabetic ketoacidosis and cerebral edema: a case report. Neurosurgery — Cremer OL, van Dijk GW, van Wensen E, et al Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury.
Crit Care Med — Steiner LA, Czosnyka M, Piechnik SK, et al Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Wood E, Go-Wingkun J, Luisiri A, et al Symptomatic cerebral swelling complicating diabetic ketoacidosis documented by intraventricular pressure monitoring: survival without neurologic sequela.
Pediatr Emerg Care — Qureshi AI, Suarez JI Use of hypertonic saline solutions in treatment of cerebral edema and intracranial hypertension. Kamat P, Vats A, Gross M, et al Use of hypertonic saline in the treatment of altered mental status associated with diabetic ketoacidosis. Download references. Correspondence to L. Reprints and Permissions. Bailly-Salin, J. Download citation. Received : 14 March Accepted : 28 May Published : 16 July Issue Date : September Search SpringerLink Search.
Abstract Diabetic ketoacidosis is the most common cause of morbidity and mortality in children with type I diabetes mellitus. Chevret Authors J. Bailly-Salin View author publications. You can also search for this author in PubMed Google Scholar. View author publications. Rights and permissions Reprints and Permissions. About this article Cite this article Bailly-Salin, J.
Œdème cérébral aigu au cours de l’acidocétose diabétique de l’enfant
Please, ask your free registration to nkooamvenes gmail. Then, login and select " new submission ". The aim of our study was to describe epidemiology, evolution and take care of the Acute Renal Failure ARF during diabetic ketoacidosis in intensive care. This was a retrospective study on 6 months January to July conduced in the medical intensive care unit of the University Hospital Ibn Rochd of Casablanca. Were included patients admitted for diabetic ketoacidosis. Of these Personal history of diabetes was found in
Acidocétose diabétique chez l’enfant: aspects épidémiologiques et pronostiques
La crase est normale. Rev Med Suisse ; volume 1. Metabolic acidosis in the alcoholic : A pathophysiologic approach. Metabolism ; The use of the urinary anion gap in the diagnosis of hyperchloremic metabolic acidosis.