INVISIBLE DERMATOSES PDF

It is understandable that clinically normal skin may show abnormalities when examined with the light microscope, but paradoxical that biopsy of a clinically significant skin disorder may show a histologic picture that looks like normal skin. From the perspective of the dermatopathologist, the invisible dermatoses are clinically evident skin diseases that show a histologic picture resembling normal skin. A strategy for approaching the problem of the invisible dermatoses is to first examine the epidermis for fungi, cornoid lamellae disseminated superficial actinic porokeratosis , and absence of the granular layer dominant ichthyosis vulgaris. The cutis is then studied for hyalin deposition macular amyloidosis , mast cells, microfilaria, dermal melanocytosis, silver granules, and absence of sweat glands anhidrotic ectodermal dysplasia.

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It is understandable that clinically normal skin may show abnormalities when examined with the light microscope, but paradoxical that biopsy of a clinically significant skin disorder may show a histologic picture that looks like normal skin.

From the perspective of the dermatopathologist, the invisible dermatoses are clinically evident skin diseases that show a histologic picture resembling normal skin. A strategy for approaching the problem of the invisible dermatoses is to first examine the epidermis for fungi, cornoid lamellae disseminated superficial actinic porokeratosis , and absence of the granular layer dominant ichthyosis vulgaris. The cutis is then studied for hyalin deposition macular amyloidosis , mast cells, microfilaria, dermal melanocytosis, silver granules, and absence of sweat glands anhidrotic ectodermal dysplasia.

Special stains may be required to uncover conditions like anetoderma and nevus elasticus. Finally, technical problems should be considered, including sampling errors and mixup of specimens, either by the clinician or the laboratory. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.

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Full-text links Cite Favorites. Abstract It is understandable that clinically normal skin may show abnormalities when examined with the light microscope, but paradoxical that biopsy of a clinically significant skin disorder may show a histologic picture that looks like normal skin. Similar articles Invisible dermatoses. Mysore V. Indian J Dermatol Venereol Leprol. PMID: Review. Invisible dermatoses from the perspective of the dermatopathologist: new observations.

Tomasini C. G Ital Dermatol Venereol. Epub Jul Porokeratotic eccrine ostial and dermal duct naevus. Abell E, Read SI. Abell E, et al. Br J Dermatol. PMID: Linear porokeratosis and other linear cutaneous eruptions of childhood. Cox GF, Jarratt M. Cox GF, et al. Am J Dis Child. Intertriginous dermatoses. Common puzzling problems. Brophy MC, et al. Postgrad Med. Show more similar articles See all similar articles. El Hanbuli HM, et al. J Microsc Ultrastruct. The significance of clinicopathologic correlation].

Kutzner H, et al. MeSH terms Biopsy Actions. Diagnosis, Differential Actions. Humans Actions. Full-text links [x] Elsevier Science. Copy Download.

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Invisible Dermatoses

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Read article at publisher's site DOI : To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation. Mysore V.

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The Invisible Dermatoses

Click on image for details. The term invisible dermatoses has been used in two contexts: a Diseases, with out definite clinical features, and are therefore "invisible" to the clinician, but yet can be diagnosed by special investigations. Diagnosis of such diseases represents a great challenge to both the dermatologist and dermatopathologist. This article discusses such diseases and offers clues and tools for their diagnosis. Diagnosis of such 'Invisible dermatoses' needs proper awareness, recognition of subtle features, special stains, special investigations such as immunofluorescence and histochemistry and proper clinicopathological correlation.

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Invisible dermatoses from the perspective of the dermatopathologist: new observations.

The eye is an unreliable instrument for judging the normalcy of skin. In chronic widespread dermatoses, the uninvolved skin is at least physiologically abnormal. Recently healed skin is always abnormal. Recognition of occult changes will have a substantial impact on the prevention and treatment of diseases of the skin.

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